abstract |
A complex comprising a purified polypeptide comprising an in vitro carbamylated human alpha-1-antitrypsin (hA1AT), or a fragment thereof, and one or more human anti-CarP antibodies, wherein the fragment comprises a partial sequence containing lysine of 5 or more contiguous amino acids from hA1AT, and wherein the anti-CarP antibody specifically recognizes hA1AT, or a fragment thereof, in its carbamylated form, but not in its non-carbamylated form. |