| abstract |
An injection applicator comprising an injectable composition, the injectable composition comprises a compressed silk fibroin foam having an interconnected pore structure and a porosity of at least 50% for use in a method of repairing or augmenting tissue in a subject, wherein the foam is compressed prior to injection and expands when released from compression after injection into the tissue, and retains at least 1% of its original expanded volume within the tissue for at least 2 weeks, in wherein the foam and the injection applicator have dimensions relative to each other to provide compression of the foam as it is within the injection applicator prior to injection. |