http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2790398-T3

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assignee http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bbf56476a41dd77e91c02bdfe8db31d7
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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6806
filingDate 2010-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ae750ba3400c569547a52b10341ce05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f34a021422d626523a58e690abcaa4b0
publicationDate 2020-10-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2790398-T3
titleOfInvention Preservation of fetal nucleic acids in maternal plasma
abstract A non-invasive prenatal screening method for the identification of fetal characteristics that includes the steps of: - contacting a sample of extracted maternal blood that includes a plurality of blood cells with a protective agent for nucleic acids in a sufficient amount and time so as to prevent blood cells from (i) releasing genomic nucleic acids into the blood sample and (ii) experiencing nuclease activity that degrades fetal nucleic acid; wherein said nucleic acid protecting agent comprises imidazolidinylurea, ethylenediaminetetraacetic acid and glycine; - isolation of fetal nucleic acids from the maternal blood sample; and - analysis of isolated fetal nucleic acids to identify a fetal characteristic.
priorityDate 2009-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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