http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2788692-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_efbdde5787012bf08cbccb02d611252a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00711 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00317 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00702 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00722 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0829 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2219-00689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0654 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-5085 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-6452 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C40B60-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-648 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B60-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-04 |
| filingDate | 2015-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ca97be897501f6a7e0b949cd3a8bde5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0173ec8569294db7bffd2c6e8780cc90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe66c90982c4b04ee3160bdc163e8004 |
| publicationDate | 2020-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2788692-T3 |
| titleOfInvention | Synthesis sequencing using pulse read optics |
| abstract | A system for photocleaving and screening nucleotide analogs comprising: a) a substrate comprising a plurality of wells each containing, or configured to contain, a reaction mixture comprising a template nucleic acid, a polymerase, an annealed primer with said template and a first nucleotide analog, wherein said primer comprises a 3' terminal nucleotide analog with a photolabile blocking group that terminates chain extension, and wherein said first nucleotide analog comprises: i) a first detectable moiety, and ii) a photolabile blocking group that terminates chain extension; and b) a light system component comprising: i) a light source in optical communication with said plurality of wells providing: A) photocleavage light input that cleaves said photolabile blocking group when it is part of said primer; and B) scanning input light producing an optical signal of said first detectable moiety after said first nucleotide analog is added to said primer by said polymerase; and ii) a light control component that activates said light source such that a plurality of unlock-scan cycles are generated, wherein each of said unlock-scan cycles comprises an initial unlock time period wherein at least a portion of said photocleavage light input is passed to said plurality of wells, and a following scan time period in which at least a portion of said scanning light input is passed to said plurality of wells, and wherein said unlock time period is between 25 and 150 ms and said scan time is at least 200 ms. |
| priorityDate | 2014-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.