| abstract |
A compound or a pharmaceutically acceptable salt thereof for use in treating a disease, disorder or condition selected from the group consisting of ischemic reperfusion injury, hyperinsulinemia, hyperlipidemia, glycemia, glucose tolerance, insulin sensitivity, adiposity , insulin resistance, obesity, diabetes, neurodegeneration, traumatic brain injury, heart failure, Parkinson's disease; wherein said compound is selected from the group consisting of: ** (See formula) ** (2-fluorophenyl) {6 - [(2-fluorophenyl) amino] (1,2,5-oxadiazolo [3,4- e] pyrazin-5-yl)} amine ** (See formula) ** (4-chlorophenyl) {6 - [(4-chlorophenyl) amino] (1,2,5-oxadiazolo [3,4-e] pyrazin -5-yl)} amine ** (See formula) ** (4-fluorophenyl) {6 - [(4-fluorophenyl) amino] (1,2,5-oxadiazolo [3,4-e] pyrazin-5- il)} amine ** (See formula) ** |