| abstract |
The present invention relates to a polypeptide comprising the fragment SEQ ID No .: 2 of the peptide GSE24.2 (SEQ ID No.:1) and capable of reducing the production of free radicals and / or the damage in the structure of the DNA of a cell, optionally being able to comprise nuclear localization sequences.In addition, the invention also relates to a polynucleotide and a vector, which comprise sequences encoding said polypeptide, as well as a pharmaceutical composition comprising the polypeptide, polynucleotide and / or vector previous. The present invention also refers to the applications of the polypeptide, such as the use to treat and / or prevent diseases caused by increased oxidative stress and / or damage to cellular DNA, such as ataxia, telangectasia or dyskeratosis congenita, or use in tissue engineering and cell culture to improve their viability. |