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filingDate 2015-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2780931-T3
titleOfInvention Double-layer composite material formation method, double-layer composite material therefore biomedical equipment containing the double-layer composite material
abstract A method of forming a double layer composite material, wherein the double layer composite material is a biomedical material, comprising: coating a barrier film layer forming material on a surface of a porous scaffold layer to form a double layer intermediate product; and drying the double layer intermediate product to form a double layer composite material comprising the porous scaffold layer and a barrier film layer, wherein the porous scaffold layer and the barrier film layer are inseparable from each other. , and wherein a method of forming the porous scaffold layer comprises: mixing at least a first biodegradable polymer with a first solvent at a stirring speed of 3500-12000 rpm, at 4-10 ° C, for 90-180 minutes, to form a slurry, wherein the at least one first biodegradable polymer is selected from a group consisting of collagen, gelatin, chitosan, and a combination of collagen, gelatin, or chitosan and hyaluronic acid; place the grout in a mold and freeze the grout; carry out a lyophilization procedure on the grout to remove the water molecules and obtain a scaffold body; and performing a vacuum heating process on the scaffold body to dehydrate and cross-link the scaffold body to form the porous scaffold layer, and wherein a method of forming the barrier film layer-forming material comprises: mixing a second biodegradable polymer with a second solvent and then allowing it to stand to form a gel, wherein the second biodegradable polymer is selected from a group consisting of collagen, gelatin, chitosan, and hyaluronic acid; and agitating the gel to a homogeneous degree to form the barrier film layer-forming material.
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