| abstract |
A compound, or a salt thereof, where the compound is represented by Formula (I) ** (See formula) ** where Y is N or C-Ra; Ra is hydrogen or C1-C4 alkyl; Rb is hydrogen, C1-C4 alkyl, C1-C4 alkoxy, hydroxy, cyano, halogen, C1-C4 trihaloalkyl or C1-C4 trihaloalkoxy; Rc and Rd are each, independently, hydrogen, C1-C4 alkyl, C1-C4 alkoxy, hydroxy, C1-C4 trihaloalkyl, C1-C4 trihaloalkoxy, or heteroaryl; A is a 6-membered heteroaryl having 1-3 ring nitrogen atoms, where the 6-membered heteroaryl is substituted with 0, 1, or 2 substituents independently selected from oxo, C1-C4 alkyl, mono- and di (C1-alkyl). C4) amino, hydroxy (C1-C4 alkyl) amino, hydroxyalkyl C1-C4, amino C1-C4 alkyl and mono- and di (C1-C4 alkyl) amino (C1-C4 alkyl); or A is a 5-membered heteroaryl having 1-3 ring heteroatoms independently selected from N, O, and S and substituted with 0, 1 or 2 substituents independently selected from C1-C4 alkyl, hydroxyl, mono- and di (C1-alkyl). C4) amino, hydroxy (C1-C4 alkyl) amino, hydroxyalkyl C1-C4, amino C1-C4 alkyl and mono- and di (C1-C4 alkyl) amino (C1-C4 alkyl); or A and Rc, together with the atoms to which they are attached, form a 6-membered aryl with 0, 1 or 2 substituents independently selected from cyano, halogen, hydroxy, C1-C4 alkyl, C2-C4 alkenyl, C2-alkynyl. C4, C1-C4 alkoxy and C1-C4 alkoxy substituted with hydroxy, C1-C4 alkoxy, amino and mono- and di (C1-C4 alkyl) amino; B is selected from ** (See formula) ** where Z is NH or N (Me), or where B is selected from ** (See formula) ** |