http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2777173-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8828412a08c427cf0e753b98d7339754 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-755 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-00 |
| filingDate | 2012-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_717c5158a13ca60b1e3b97f9b336f27c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_74ee5584df4f73f1c5f3f7cb4820bc1d |
| publicationDate | 2020-08-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2777173-T3 |
| titleOfInvention | A procedure to increase the productivity of eukaryotic cells in the production of recombinant FVIII |
| abstract | A method to increase the productivity, in particular the cell-specific productivity, of recombinant factor VIII (rFVIII) produced in a eukaryotic cell suspension during the cultivation of said eukaryotic cell suspension in a culture medium containing not more than 500 μM CaCl2, at least one non-ionic detergent and other nutritional components necessary for cells to grow and produce rFVIII, characterized in that said cell suspension is a suspension of human cells and is cultured under conditions that induce a shear stress through mechanical means directly to the human cell suspension by adding a power density of 50 W / m3 to 1000 W / m3. |
| priorityDate | 2011-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 27.