http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2775522-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8c1ee19e6efdf91c1bf88bde9e9845ef |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-10 |
| filingDate | 2016-10-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc17392ca7cb3999c32ec3af595cd211 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ccef1a17b8a15e31e898b29837a08987 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2ef5d661ee429f4963e964b92e86e74b |
| publicationDate | 2020-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2775522-T3 |
| titleOfInvention | Oxa-diazaspiro compounds that have activity against pain |
| abstract | A compound of the general Formula (I): ** (See formula) ** where R1 is ** (See formula) ** m is 1, 2, 3, 4 or 5; n is 0, 1, 2, 3, 4, or 5; p is 0 or 1; q is 0, 1 or 2; r is 0, 1 or 2; X is a bond, -C (RxRx ') -, -C (O) -, -O-, -C (O) NR7-, -NR7C (O) - or -C (O) O-; where Rx is selected from halogen or substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl and -OR7; Rx 'is selected from hydrogen, halogen or substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, and substituted or unsubstituted C2-6 alkynyl; R7 is selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, and unsubstituted or substituted C2-6 alkynyl; Y is -CH2- or -C (O) -; R1 'is selected from substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heterocyclyl; R2 is selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, and substituted or unsubstituted heterocyclyl , R3 is selected from substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, and substituted or unsubstituted C2-6 alkynyl; R3 'is selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, and substituted or unsubstituted C2-6 alkynyl; alternatively, R3 and R3 'may form, together with the carbon atom to which they are attached, a substituted or unsubstituted cycloalkyl; R4 and R4 'are independently selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl, -CHOR9 and -C (O) OR9; where R9 is selected from hydrogen, substituted or unsubstituted C1-9 alkyl, substituted or unsubstituted C2-9 alkenyl, and unsubstituted or substituted C2-9 alkynyl; R5 and R5 'are independently selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aryl, heterocyclyl substituted or unsubstituted, -CHOR8 and -C (O) OR8; where R8 is selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, and substituted or unsubstituted C2-6 alkynyl; alternatively, R5 and R5 'taken together with the connecting C atom may form a substituted or unsubstituted cycloalkyl, or a substituted or unsubstituted heterocyclyl; R6 and R6 'are independently selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, substituted or unsubstituted C2-6 alkynyl, -CHOR10 and -C (O) OR10; where R10 is selected from hydrogen, substituted or unsubstituted C1-6 alkyl, substituted or unsubstituted C2-6 alkenyl, and substituted or unsubstituted C2-6 alkynyl; optionally in the form of one of the stereoisomers, preferably enantiomers or diastereomers, a racemate or in the form of a mixture of at least two of the stereoisomers, preferably enantiomers and / or diastereomers, in any mixing ratio, or one of their corresponding salts or one of its corresponding solvates; applying the following conditions: - q is not 1 when r is 1; - when Y is -C (O) -, then R1 is not. ** (See formula) ** |
| priorityDate | 2015-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 225.