Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e13cf25eb1bef6199475314477618b46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d9cf7ff1f08310f0557c06b9a0f910a9 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
filingDate |
2016-05-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cc346a290898959f25c6ac65ef0d4fc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ca2f15f91f87818bd89c4fb9a012e0fb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb38af886ec5cda6585d819e63729687 |
publicationDate |
2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2774178-T3 |
titleOfInvention |
Synthesis of 1h-pyrrolo [2,3-B] pyridine derivatives that modulate kinases |
abstract |
A process for the preparation of a compound of formula I: ** (See formula) ** or a salt thereof, comprising: contacting a compound of formula IV: ** (See formula) ** or a salt of this, with a compound of formula V: ** (See formula) ** or a salt thereof, under reductive amination conditions comprising triethylsilane and trifluoroacetic acid; sodium borohydride and benzoic acid; or sodium triacetoxyborohydride and acetic acid, to provide the compound of formula I or a salt thereof. |
priorityDate |
2015-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |