| abstract |
A compound comprising a modified antisense oligonucleotide consisting of 12 to 30 linked nucleosides, wherein the modified antisense oligonucleotide is directed to an angiotensinogen (AGT) nucleic acid, for use in treating an animal having a disease, disorder and/or RAS pathway-related condition, wherein the RAS pathway-related disease, disorder or condition is resistant hypertension. |