Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef3f170ba9716cbc469ccf7debf23e8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_61f88efcda59d7062a4252ecf6886f58 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-525 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 |
filingDate |
2014-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf28d65db9bcb940fe92e8a6501e9a2d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6c917efb3f732c90992c255a7964f100 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21fce2920cabdf74f70046a9c524f8d9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_801de45c465ddffd4c63b9ac771e3e24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8f635b300744e2a7a8f2bb49c4baed6f |
publicationDate |
2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2773309-T3 |
titleOfInvention |
Conformationally stabilized RSV pre-fusion F proteins |
abstract |
RSV F polypeptide, protein or protein complex comprising: (a) an amino acid sequence having at least 70% sequence identity with amino acid residues 1-513 of SEQ ID NO.1 (RSV type A) or amino acid residues 1-513 of SEQ ID NO.3 (RSV type B), wherein the amino acid sequence comprises a point mutation to tyrosine at an amino acid position equivalent to position 226 in SEQ ID NO.1 or SEQ ID NO.3 and a tyrosine at an amino acid position equivalent to position 198 in SEQ ID NO.1 or SEQ ID NO.3, and (b) a trimerization domain, in which the polypeptide, protein or protein complex is capable of folding into the pre-F conformation. |
priorityDate |
2013-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |