http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2773148-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f85b08f8307c2c093183b1254729485 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0048 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-724 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-662 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-00 |
| filingDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2d9ea9daf47701bb593ad5d998f8983c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55626124593b138984ced0438f15619c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f36e04650e0224b9282d144cce9b0448 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e3aacbd213a2560510989991fa1a18d |
| publicationDate | 2020-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2773148-T3 |
| titleOfInvention | Aminophosphin derivatives for the prevention and treatment of eye pain |
| abstract | Compounds that respond to formula (I): (I) R1-NH-CH (R2) -P (= O) (OH) -CH2-C (R3) (R4) -CONH-C (R5) (R6) -COOR7 in which: R1 represents - a hydrogen - an (acyloxy) alkyl carbamate group -C (= O) -OC (R) (R ') - OC (= O) -R' 'in which R and R 'represent, independently of each other, a hydrogen, an alkyl group and R' 'represents an alkyl group. R2 represents: - a hydrocarbon chain, saturated or unsaturated, straight or branched, comprising from 1 to 6 carbon atoms R3 and R4 represent independently of each other: - a hydrogen - a phenyl or benzyl group, optionally substituted in the phenyl nucleus by: * 1 to 5 halogen atoms in particular fluorine or bromine. * a radical OH, SH, OR "or SR", R "having the same definition as above. * an amino group optionally mono- or di-substituted by an aliphatic, cyclic or linear group, with 1 to 6 carbon atoms. * a trifluoromethyl group * an aromatic or heteroaromatic group of 5 or 6 atoms - a heteroaromatic group of 5 or 6 atoms, containing 1 or 2 heteroatom (s) selected from oxygen, nitrogen or sulfur, the atoms of sulfur and nitrogen be oxidized as S-oxide or N-oxide. - a methylene substituted by a heterocycle of 5 or 6 atoms, aromatic or saturated, the heteroatom being an oxygen, a nitrogen or a sulfur, the nitrogen and sulfur atoms being able to be oxidized in the form of N-oxide or S-oxide R3 and R4 do not simultaneously represent a hydrogen atom. R5 and R6 represent independently of each other - a hydrogen atom - a saturated or unsaturated, linear or branched hydrocarbon chain of 1 to 6 carbon atoms R7 represents - a hydrogen - a radical CH2COOR '' 'or CH (CH3) COOR' '', where R '' '* represents a saturated hydrocarbon chain of 1 to 6 carbon atoms, optionally substituted by a C1 to C3 alkoxy group, * a C5 to C8 cycloalkyl group * a phenyl, benzyl, heteroaromatic or alkyl group heteroaromatic. - a group CH (R) O-C (O) OR 'or CH (R) OC (O) R' in which R and R 'have the same definitions as above; or a pharmaceutically acceptable salt of these compounds for use in the treatment and / or prevention of eye pain. |
| priorityDate | 2015-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.