http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2771856-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_14aa989a900720bdceed4eca32fc5681 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2371-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2400-06 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08L71-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 |
| filingDate | 2015-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d1ef6e39c5ea32aa127a0e70e6bd83b |
| publicationDate | 2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2771856-T3 |
| titleOfInvention | Method of preparing a hydrogel, hydrogel and formulation for vehicles and / or connective tissue substitute obtained using said method |
| abstract | A method of preparing a hydrogel for use as a connective tissue vehicle and / or substitute, comprising the steps of: - providing a predetermined amount of an aqueous solution; - adding a predetermined amount of polymerization regulating agent to said aqueous solution, to regulate the polymerization of a first water-soluble polymer polymerizable by electromagnetic radiation; - adding, hydrating and / or solubilizing a predetermined amount of said first water-soluble polymer in said aqueous solution, to obtain a mixture; - adding, hydrating and / or solubilizing a second water-soluble polymer polymerizable by electromagnetic radiation, different from the first, in said mixture; - applying electromagnetic radiation of predetermined frequency to said mixture, to achieve the polymerization of said first polymer and said second polymer with a predetermined viscosity, and to obtain a sterile hydrogel; characterized in that said second water-soluble polymer is not reactive with said regulating agent and has a degree of polymerization that varies according to the intermolecular steric hindrance of the chains of said first polymer, said first water-soluble polymer being selected from among a first group comprising polyethylene glycol (PEG) or between a second group comprising polyethylene oxide (PEO), the percentage by weight of said first water-soluble polymer varying from 1% to 20%, based on the total weight of the hydrogel, said second water-soluble polymer being selected from the group comprising hydroxyethylcellulose (HEC), hydroxypropylmethylcellulose (HPMC), ethylcellulose (EC), methylcellulose (MC), varying the percentage by weight of said second water-soluble polymer of a 0.1% to 10%, preferably 0.5% to 5%, based on the total weight of the hydrogel, said regulating agent being selected from the group comprising asco acid rbic, carotenoids, lipoic acid, vitamins E, D, B and glutathione, the concentration of said regulating agent in the mixture being 100 mM or less. |
| priorityDate | 2014-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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