| abstract |
An antitumor composition based on a C6-C18 acylated derivative of hyaluronic acid according to the general formula (I) ** Formula ** where R is H + or Na +, and where R1 is H or -C (= O) CxHy or -C ( = O) CH = CH-het, where x is an integer within the range of 5-17 and y is an integer within the range of 11-35 and CxHy is a C5-C17 straight or branched, saturated or unsaturated chain and het is a heterocyclic or heteroaromatic residue, optionally containing N, S or O atoms, wherein in at least one repeating unit one or more R1 is -C (= O) CxHy or -C (= O) CH = CH- het, and where n is within the range of 12 to 4000, characterized in that it also contains inorganic nanoparticles with the stabilizer oleic acid, where the inorganic nanoparticles are selected from the group consisting of superparamagnetic nanoparticles, up-conversion nanoparticles or oxide nanoparticles. zinc, especially superparamagnetic nanoparticles. |