abstract |
A pharmaceutical composition comprising an oxidized phospholipid having a structure according to formula (I): ** Formula ** wherein R1 is linear or branched C14-C20 alkyl; R3 is selected from phosphorylethanolamine, phosphorylcholine, phosphorylethanolamine-N-glutaric acid and phosphorylserine; R5 is a member selected from H, a negative charge, and linear or branched C1-C6 alkyl; and X1 is C2-C6 alkylene, a polyethylene glycol or poloxamer as a thermosetting carrier, and talc as a release agent, wherein the weight ratio of said release agent to said oxidized phospholipid is from about 1: 5 to about 5: 1. |