http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2765510-T3
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a8c997f15e4c1f6392a7ea329823eb1 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate | 2015-09-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31da1a08c4fa21098ccc1982a004fceb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d3bd57fff6b135879b3b85e3fe1e1ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26dd2d5bf560ba728b3af1708d4b817d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e90164318f92cd337f48c8338c65c230 |
publicationDate | 2020-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2765510-T3 |
titleOfInvention | Novel imidazopyridazine compounds and their use |
abstract | A compound of formula (I): ** (See formula) ** and / or a pharmaceutically acceptable salt thereof, and / or its solvates, racemic mixture, enantiomers, diastereomers, and tautomers, in which Ar is aryl, said aryl is a carbocyclic hydrocarbon radical of a monocyclic ring or fused rings containing 6-12 ring carbon atoms, in which at least one ring is aromatic and none of the other rings is heteroaryl; or heteroaryl, said heteroaryl is a monocyclic aromatic hydrocarbon radical having 5, 6 or 7 ring atoms, and containing 1 or 2 heteroatoms independently chosen from N, O, and S in the ring, the remaining ring atoms being carbon; or a bicyclic aromatic hydrocarbon radical having 9 or 10 ring atoms, and containing 1, 2, 3 or 4 heteroatoms independently chosen from N, O, and S in the rings, the remaining ring atoms being carbon, in which at least one of the rings is aromatic; when the total number of S and O atoms in the heteroaryl group exceeds 1, those heteroatoms are not adjacent to each other, and said heteroaryl group also includes those in which the N heteroatom appears as Noxide; each of said aryl and heteroaryl is optionally substituted with one or more groups selected from deuterium, halo, -CN, -OH, -SH, C1-6 alkyl, C1-6 haloalkyl, - (C1-6 alkyl) OH , and -S (O) 2 (C1-6 alkyl); W is chosen from heteroaryl and -N (R3) heteroaryl, wherein said heteroaryl is a nitrogen-containing monocyclic aromatic hydrocarbon radical having 5, 6, or 7 ring atoms, and containing 1 or 2 heteroatoms, wherein the heteroatom or heteroatoms are nitrogen atoms, the remaining ring atoms being carbon; or a nitrogen-containing bicyclic aromatic hydrocarbon radical having 9 or 10 ring atoms, and containing 1, 2, 3, or 4 heteroatoms, wherein the heteroatom or heteroatoms are nitrogen atoms, the remaining ring atoms being carbon, in the that at least one of the rings is aromatic; and said heteroaryl group also includes those in which the N heteroatom appears as N-oxide, and said heteroaryl is optionally substituted with one or more groups selected from halo, -CN, -OH, -SH, C1-6 alkyl, -NH2, -NH (C1-6 alkyl), -N (C1-6 alkyl) (C1-6 alkyl), -COOH, -C (O) NH2, -C (O) NH (C1 alkyl) -6), -C (O) N (C1-6 alkyl) (C1-6 alkyl), phenyl, and 5- or 6-membered heteroaryl; wherein said 5- or 6-membered heteroaryl is a monocyclic aromatic hydrocarbon radical having 5 or 6 ring atoms, and containing 1, 2, or 3 heteroatoms independently chosen from N, O, and S in the ring, the ring atoms being remaining carbon; when the total number of S and O atoms in the heteroaryl group exceeds 1, those heteroatoms are not adjacent to each other, and each of said phenyl or said 5- or 6-membered heteroaryl as a substituent of W is optionally substituted with one or more groups selected from halo, -OH, -SH, C1-6 alkyl, and -O (C1-6 alkyl); R1 is independently chosen from H, halo, and C1-6 alkyl; R2 is chosen from C1-6 alkyl; R3 is H or C1-6 alkyl; m is 1 or 2. |
priorityDate | 2014-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 294.