Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1bceb71676971f1383ae2a7e5ccaa7da |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4164 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4166 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6888 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6897 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-543 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2869 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6886 |
filingDate |
2013-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2020-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62153fe38e9e1b0482d6403dd565b65d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_531fb8e820125e4dc1137b673efa8ffc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1b1a82a5c38106f5b611b5909a9af1c7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_05c99847e0e1f0dd447228963dd730f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_761d014bfb4c029499ddd45e93c35feb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1058459d43c8123275ac544ae48258c9 |
publicationDate |
2020-06-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
ES-2764381-T3 |
titleOfInvention |
Methods and compositions for determining resistance to androgen receptor therapy |
abstract |
A method of determining whether a subject is or will become less sensitive to therapy with a first or second generation androgen receptor (AR) antagonist, comprising: (a) analyzing a sample containing a nucleic acid molecule that encodes an AR polypeptide from the subject to determine whether the encoded AR polypeptide is modified at an amino acid position corresponding to amino acid position 876 of the amino acid sequence set forth in SEQ ID NO: 1; and (b) characterizing the subject as resistant or will become resistant to therapy with a first or second generation AR antagonist if the subject has the modification. |
priorityDate |
2012-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |