http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2763121-T3

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grantDate 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2763121-T3
titleOfInvention Topical administration method
abstract A method for topical drop administration of a liquid composition (2), comprising the steps of: a) providing a drop dispenser (1), comprising - a container part (1B) with an inner volume partially filled with the liquid composition (2) and a gaseous phase (3) that fills the rest of the interior volume at ambient pressure, the container part (1B) having a movable section (1C) and optionally a substantially stationary section, and - a dropper part (1A ) in physical connection and in fluid communication with the interior volume of the container part (1B), which comprises an outlet channel (5), which connects the interior volume of the container part (1B) to the environment; b) exerting a first force to the movable section (1C) of the container part (1B) of the drop dispenser (1) while keeping the drop dispenser (1) in a vertical position in which the outlet channel (5) it is not in contact with the liquid composition (2), thus reducing the internal volume of the container part (1B) and forcing the gaseous phase (3) of the internal volume at least partially out of the drop dispenser (1) to the environment; c) inverting the drop dispenser (1) to an inverted position in which the liquid composition (2) is in contact with the outlet channel (5); d) releasing said first force from the movable section (1C) of the container part (1B) at least partially, thus reducing the pressure within the container part (1B) below ambient pressure; and e) exert a second force to the movable section (1C) of the container part (1B), while still keeping the drop dispenser in the inverted position in which the liquid composition (2) is in contact with the outlet channel ( 5), thus raising the pressure within the interior volume of the container part (1B) above ambient pressure and releasing the liquid composition (2) in drops from the dropper part (1A) of the drop dispenser (1).
priorityDate 2016-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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