http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2761173-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6cd9e39dc0670ddec04d9d27619da385 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ff81a650b70e913d3b2524b45e4c7320 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6491 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-80 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C49-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P39-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C235-78 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C235-78 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C49-255 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C225-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C69-738 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N37-02 |
| filingDate | 2010-05-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4c47364fa78dc76391f593e8d7bbe80b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b89074389c08d529719db08891f4401c |
| publicationDate | 2020-05-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2761173-T3 |
| titleOfInvention | Curcumin analogues as zinc chelators and their uses |
| abstract | A compound having the structure ** Formula ** wherein the α and β bond are each, independently, present or absent; X is CR5 or N; Y is CR10 or N; R1 is -C (O) R14, -C (S) R14, or -C (= NH) R14, where R14 is C2-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, heteroaryl, heterocyclyl, methoxy , -OR15, -NR16R17, or ** Formula ** wherein R15 is H, C3-10 alkyl, C2-10 alkenyl, C2-10 alkynyl; R16 and R17 are each, independently, H, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl, or heterocyclyl; R18, R19, R21 and R22 are each independently H, halogen, -NO2, -CN, -NR23R24, -SR23, -SO2R23, -CO2R23, -OR25, CF3, -SOR23, -POR23, -C (= S) R23, -C (= NH) R23, -C (= NR24) R23, -C (= N) R23, -P (= O) (OR23) (OR24), -P (OR23) (OR24), -C (= S) R23, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl or heterocyclyl; wherein R23, R24, and R25 are each, independently, H, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl, or heterocyclyl; R20 is halogen, -NO2, -CN, -NR26R27, CF3, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl or heterocyclyl; wherein R26 and R27 are each, independently, H, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl, or heterocyclyl; R2, R3, R4, R5, R6, R7, R8, R9, R10 and R11 are each independently H, halogen, -NO2, -CN, -NR28R29, -NHR2sR29 +, -SR28, -SO2R28, -OR28, -CO2R28 , CF3, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl, aryl, heteroaryl or heterocyclyl; wherein R28 and R29 are each H, CF3, C1-10 alkyl, C2-10 alkenyl, C2-10 alkynyl or -C (= O) -heterocyclyl; and wherein each occurrence of alkyl, alkenyl, or alkynyl is branched or unbranched, unsubstituted or substituted with halogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, tert-butyl, trifluoromethyl, hydroxy, methoxy, ethoxy , n-propoxy, isopropoxy, phenoxy, benzyloxy, p-trifluoromethylbenzyloxy, trifluoromethanesulfonyl, methanesulfonyl, p-toluenesulfonyl, nitro, nitrosyl, mercapto, methylsulfanyl, ethylsulfanyl, propylsulfanyl, ethylamino, carboxylamino, diethylsulfanyl, ethylamino, carboxylamino, diethylsulfanyl, methylamino, amino, diethylamino, diethylamino, or diethylamino, or diethylamino, or a salt thereof. |
| priorityDate | 2009-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 613.