| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ae10212794160b34478f0d05b6ab6fd7 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-51 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-179
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-71
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-721
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-72
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate |
2013-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4570621de5555145e794fe8a495f94a2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_043bcc780b0a769325796973f3c61789
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff4d6d4812270aff7ff2b044276aa0bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d39cf1b8c2e6cc843e2b60a83b951b94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3f5789d580761e4e3f56fa4febe79c37
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_973c325cf7d9c6376080341dd4349236
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_298b77c8e14d720bb54b03e1baedc151 |
| publicationDate |
2020-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2753811-T3 |
| titleOfInvention |
Biomarker for use in treating anemia |
| abstract |
An activin type II receptor inhibitor for use in a method for treating anemia, beta thalassemia, or for increasing levels of red blood cells or orthochromatic erythroblasts (Ery-C) in a subject in need thereof, wherein the method comprises : (a) assess the level and / or activity of GDF11 in a tissue sample from the subject, and (b) if the level and / or activity of GDF11 is elevated above the normal level and / or activity of GDF11, administer an inhibitor of the activin type II receptor to the subject, wherein the activin type II receptor inhibitor is a polypeptide comprising an amino acid sequence selected from the group consisting of: ** Table ** wherein the activin type II receptor inhibitor it is a polypeptide comprising the extracellular domain of the activin type IIA receptor bound to the Fc portion of an antibody; or wherein the activin type II receptor inhibitor is a polypeptide comprising the extracellular domain of the activin type IIB receptor bound to the Fc portion of an antibody. |
| priorityDate |
2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |