http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2752229-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_893a226936dbbf0db92db7204e7a6345 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2002-00 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N47-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-238 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L3-3463 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C279-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C225-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-5442 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N55-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N55-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N57-34 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C279-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N55-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N55-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N57-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N47-44 |
filingDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b21be3d9d7ceee4ab98f2b22cb8d56d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07980149a74f5992224042e371325564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ab5dd0bb8056b9bf9b0009ab97ba3bc http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_399f38b35a443e993d69de3f192e6265 |
publicationDate | 2020-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2752229-T3 |
titleOfInvention | Derivatives of 1,7-diaryl-1,6-heptadien-3,5-dione, procedure for the preparation and use of the same |
abstract | Non-therapeutic procedure for the inactivation of microorganisms, where the procedure comprises the following steps: (A) putting the microorganisms in contact with at least one photosensitizer, where the photosensitizer is at least a derivative of 1,7-diaryl-1,6- Heptadiene-3,5-dione of formula (100): ** Formula ** and / or at least one 1,7-diaryl-1,6-heptadiene-3,5-dione derivative of formula (101): * * Formula ** or respectively a pharmaceutically compatible salt and / or ester and / or a complex thereof, where the residues Q3, Q3a, Q4 and Q4a represent, respectively independent of each other, a monocyclic or substituted or unsubstituted aromatic residue polycyclic, or a monocyclic or polycyclic substituted or unsubstituted heteroaromatic moiety, where the compound of formula (100) does not contain an -OH group that is directly attached to organic residues Q3 or Q4, and where the compound of formula (101) does not contain an -OH group that is directly attached to organic residues Q3, Q3 a, Q4 or Q4a, and where K represents hydrogen or a cation, and where Mz + represents a metal cation, where z is the formal oxidation number of the metal M and z represents an integer from 1 to 7, preferably from 2 to 5, and where (a1) at least one of the Q3, Q3a, Q4 and Q4A residues, respectively independent of each other, is an unsubstituted heteroaromatic residue, monocyclic or polycyclic, which has at least 5 ring atoms, where ring atoms contain at least one carbon atom and at least one nitrogen atom, which can preferably be protonated, or (a2) at least one of the residues Q3, Q3a, Q4 and Q4a, respectively independent of each other, is substituted with at least one organic residue W1, where the at least one organic residue W1 has the general formula (4), (5), (6), (7), (8), or (9): - (C (D ) (E)) hX, (4) -A- (C (D) (E)) hX, (5) - (C (D) (E)) k-aryl- (C (D) (E)) lX, (6) -A- (C (D) (E)) k-aryl- (C (D) (E)) lX, (7) - ((C (D) (E)) mA) p- (C (D) (E)) nX, (8) -A - ((C (D) (E)) mA) p- ( C (D) (E)) nX, (9) where h represents an integer from 1 to 20, where k represents an integer from 0 to 10, where l represents an integer from 0 to 10, and where m, n, and p respectively independent of each other, represent an integer from 1 to 6, and where A, respectively independent of each other, represents oxygen or sulfur, where D and E represent, respectively independent of each other, hydrogen, halogen, GR (I), or GC (= G) -R (II), where G represents, respectively independent of each other, oxygen or sulfur, and where the residues R (I) and R (II) represent, respectively independent of each other , hydrogen, methyl, ethyl, n-propyl, n-butyl, n-pentyl, phenyl or benzyl, where phenyl and benzyl can be substituted or unsubstituted, where aryl is an aromatic group, substituted or unsubstituted, or a heteroaromatic group , substituted or unsubstituted, that does not contain a nitrogen atom, where X is, respectively independent of each other, an organic residue which (i) contains at least one neutral nitrogen atom which may be protonated or (ii) contains at least one positively charged nitrogen atom, preferably quaternary, or (iii) contains at least one positively charged phosphorous atom, preferably quaternary, and where the residues R1, R2, R3, R4 and R5 represent, respectively independent of each other, hydrogen, halogen, alkyl with 1 to 12 carbon atoms, cycloalkyl with 1 to 12 carbon atoms, alkylaryl with 1 to 12 carbon atoms C, aryl with 5 to 20 carbon atoms, ether with 2 to 12 carbon atoms or glycol with 2 to 12 carbon atoms, or where, (b) the residue R3 is an organic residue W2, where the organic residue W2 has the general formula (4), (5), (6), (7), (8), (9), or (10): - (C (D) (E)) hX, (4) -A- (C (D) (E)) hX, (5) - (C (D) (E)) k-aryl- (C (D) (E)) lX, (6) -A- (C (D) (E)) k-aryl- (C (D) (E)) lX, (7) - ((C (D) (E)) mA) p- (C (D) (E)) nX, (8 ) -A - ((C (D) (E)) mA) p- (C (D) (E)) nX, (9), - (- C (D) = C (E) -) rX, ( 10) and where optionally, at least one of the residues Q3, Q3 a, Q4 and Q4a respectively independent of each other, are substituted with at least one organic residue W1 that has the general formula (4), (5), (6), (7), (8), or (9), where h represents an integer from 1 to 20, where k is an integer from 0 to 10, where l is an integer from 0 to 10, and where m, n, p and r represent, respectively independent of each other, a number integer from 1 to 6, and where A represents, respectively independent of each other, oxygen or sulfur, where D and E represent, respectively independent of each other, hydrogen, halogen, GR (I), or GC (= G) -R (II), where G represents, respectively independent of each other, oxygen or sulfur, and where the residues R (I) and R (II) represent, respectively independent of each other, hydrogen, methyl, ethyl, n-propyl, n -butyl, n-pentyl, phenyl or benzyl, where phenyl and benzyl can be substituted or unsubstituted, where aryl is an aromatic group, substituted or unsubstituted, or a heteroaromatic group co, substituted or unsubstituted, which does not contain a nitrogen atom, where X represents, respectively independent of each other, an organic residue, which (i) contains at least one neutral nitrogen atom that may be protonated (ii) contains at least one positively charged nitrogen atom, preferably quaternary, or (iii) contains at least one positively charged phosphorous atom, preferably quaternary, and where the residues R1, R2, R4 and R5 represent, respectively independent of each other, hydrogen , halogen, alkyl with 1 to 12 carbon atoms, alkylaryl with 1 to 12 carbon atoms, aryl with 5 to 20 carbon atoms, ether with 2 to 12 carbon atoms, or glycol with 2 to 12 carbon atoms and (B) irradiating the microorganisms and at least one photosensitizer with electromagnetic radiation of suitable wavelength and energy density. |
priorityDate | 2015-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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