| abstract |
Formulation for the preparation of an instillation solution, which can be used in photodynamic therapy, which contains a hypericin bound to a polymeric complexing agent, in particular, a polyethylene glycol or a poly-Nvinylamide, in the form of an alkali metal salt, in particularly in the form of the potassium salt or the sodium salt, in which the instillation solution contains hypericin in a concentration of 9 to 40 μM, characterized in that the formulation is a stable lyophilisate, which is obtained from a aqueous solution, containing the alkali metal salt of hypericin, the complexing agent and a buffer system, in particular a phosphate buffer or a citric acid buffer solution |