http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2750209-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 |
filingDate | 2012-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7a28138814bd6a0249aadf19060cc1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_947696d6698a15d5dd340ccb328ef503 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_201a3e20a8c7b9f91105d457fde6d863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e43b06b9c190350b26d193232d971787 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_76a9f7a166028f62041d60835c2c43af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58ce8c983e1174d36c4ac1fe9f062f21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72dd26919ca6cf8a0ecddca6b16c26f6 |
publicationDate | 2020-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2750209-T3 |
titleOfInvention | Antibodies that Bind to and Block the Trigger Receptor Expressed in Myeloid Cells-1 (TREM-1) |
abstract | An antibody or fragment thereof that is capable of specifically binding to and blocking TREM-1, wherein the antibody or fragment thereof is capable of blocking activation of TREM-1 induced by PGLYRP1; wherein the antibody or fragment thereof comprises: a CDRH1 TYAMH sequence corresponding to amino acid residues 31 to 35 of SEQ ID NO: 6; a CDRH2 RIRTKSSNYATYYAASVKG sequence corresponding to amino acids 50 to 68 of SEQ ID NO: 6; and a CDRH3 DMGQRRQFAY sequence corresponding to amino acid residues 101 to 110 of SEQ ID NO: 6; and wherein the antibody or fragment thereof comprises: a CDRL1 RASESVDTFDYSFLH sequence corresponding to amino acid residues 24 to 38 of SEQ ID NO: 7; a CDRL2 RASNLES sequence corresponding to amino acid residues 54 to 60 of SEQ ID NO: 7; and a CDRL3 QQSNEDPYT sequence corresponding to amino acid residues 93 to 101 of SEQ ID NO: 7. |
priorityDate | 2012-02-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 282.