abstract |
A binding molecule that is at least bispecific comprising a first and a second binding domain, wherein (a) The first binding domain is capable of binding to the epitope cluster 3 and the epitope cluster 4 of BCMA; and (b) The second binding domain is capable of binding to CD3; and Wherein the BCMA epitope 3 cluster corresponds to amino acid residues 24 to 41 of the sequence as represented in SEQ ID NO: 1002, and the BCMA epitope 4 cluster corresponds to amino acid residues 42 to 54 of the sequence as represented in SEQ ID NO: 1002, and wherein said binding molecule is a polypeptide. |