abstract |
The compound of formula 1, ** Formula ** where A is N or CH, where Y is -O- or CH2, where R3 is an ortho or meta substituent on the pyrazolyl ring of formula 1 and is selected from the group consisting of linear or branched -C1-6alkyl, -C1-6haloalkyl, -C3-6cycloalkyl, -C1-4alkylene- C3-6cycloalkyl, a five or six membered monocyclic heterocycle with 1, 2, or three heteroatoms each independently selected from O, S, or N, a nine to 10 membered bicyclic heterocycle with 1, 2, or 3 heteroatoms each independently selected from O, S, or N, wherein R3 is optionally substituted with one, two, three or four substituents each independently selected from the group consisting of halogen (F), -C1-3alkyl, oxo, -CN in which R2 is selected from the group consisting of in -C1-3alkyl, -haloC1-3alkyl, F, Br, Cl, and the pharmaceutically acceptable salts of the compounds mentioned above. |