| abstract |
A method for the preparation of crystalline salts of AHU-377 with amines of general formula 9, where R1, R2, R3 independently signify a C1-C6 alkyl or hydrogen, characterized in that the acid AHU-377 described by formula 1 is reacts with the respective amine in at least one organic solvent or in a mixture thereof, followed by isolation of the crystalline salt of the amine with AHU-377 of formula 9 ** Formula ** and wherein the amine used is selected from the group comprising tert-butylamine, iso-propylamine, cyclohexylamine, n-propylamine and dicyclohexylamine. |