| abstract |
Nucleotide sequence encoding, from 5 'to 3', a transmembrane protein OD - (L) -TD - ED in which OD is an oligomerization domain selected from the group consisting of an isoleucine zipper and a trimerization domain of fibritin T4, L is a linker, which is optionally present, TD is a transmembrane domain derived from CD154 or any type II transmembrane protein, and ED is a CD154 extracellular domain provided that the nucleotide sequence does not comprise SEQ ID NO: 16, ie a sequence that can code for the intracellular region of CD154, nor the intracellular region of CD40. |