http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2743691-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_30beaaa993ebfd38cfa2df185ff97bb6 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-706 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7068 |
| filingDate | 2012-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_169835a6d4553c773423eb45c4830f61 |
| publicationDate | 2020-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2743691-T3 |
| titleOfInvention | Dosage regimen for sapacitabine and decitabine in combination to treat acute myeloid leukemia |
| abstract | i) Sapacitabine, or a metabolite thereof which is CNDAC; and (ii) decitabine; for use in the treatment of AML, wherein sapacitabine, or a metabolite thereof, and decitabine are administered according to a dosage regimen comprising at least one first cycle of treatment and at least one second cycle of treatment, in wherein said first course of treatment comprises administering a therapeutically effective amount of decitabine for 5 consecutive days followed by a rest period of from 3 to 5 weeks, or until treatment-related toxicities are resolved, whichever is longer; and wherein said second cycle of treatment comprises administering a therapeutically effective amount of sapacitabine, or metabolite thereof, at a dose of 100 to 400 mg b.i.d., for 3 consecutive days per week, for 2 weeks followed by a rest period 2 to 4 weeks, or until treatment-related toxicities resolve, whichever is longer. |
| priorityDate | 2011-04-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 109.