| abstract |
Cell culture comprising human cells, in which at least 26% of said human cells are endoderm cells of the proximal intestine, diverted to the dorsal pathway, positive for pancreatic-duodenal homeocage factor 1 (PDX1) that express at least one marker selected from the group consisting of CDH6, GABRA2, GRIA3, IL6R, KCNJ2, LGALS3, LGALS3 / GALIG, SERPINF2, SLC27A2, DUSP9 and SOX9, said proximal intestine endoderm cells, diverted to the dorsal pathway, positive for PDX1 cells multipotent that can differentiate into cells of the dorsal pancreatic bud. |