| abstract |
A compound of formula (IIA) or an N-oxide thereof, or a pharmaceutically acceptable salt or solvate thereof: ** Formula ** wherein E represents -CH2-; Q represents -CH2-; Z represents hydrogen or methyl; R11 represents pyrazolyl, a group which may be optionally substituted with one, two or three substituents independently selected from C1-6alkyl; R15 represents hydrogen, fluorine, chlorine, methyl, trifluoromethyl, methoxy, difluoromethoxy or trifluoromethoxy; and R16 represents hydrogen, fluorine, chlorine, cyano, methyl, trifluoromethyl, difluoromethoxy or amino. |