http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2742815-T3

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filingDate 2014-12-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_97449bb173b48235655c3c7acaaec4ef
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publicationDate 2020-02-17-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber ES-2742815-T3
titleOfInvention Antiparasitic use of isoxazoline compounds
abstract An isoxazoline compound selected from 4- [5- (3,5-dichlorophenyl) -5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] -2-methyl-N - [(2,2,2-trifluoro- ethylcarbamoyl) -methyl] -benzamide; (Z) -4- [5- (3,5-dichlorophenyl) -5-trifluoromethyl-4,5-dihydroisoxazol-3-yl] -N - [(methoxyimino) methyl] -2-methylbenzamide; 4- [5- (3,5-dichlorophenyl) -5- (trifluoromethyl) -4H-isoxazol-3-yl] -2-methyl-N- (tietan-3-yl) benzamide; 4- [5- [3-Chloro-5- (trifluoromethyl) phenyl] -4,5-dihydro-5- (trifluoromethyl) -3-isoxazolyl] -N- [2-oxo-2 - [(2,2, 2- trifluoroethyl) amino] ethyl] -1-naphthalenecarboxamide and 5- [5- (3,5-dichlorophenyl) -4,5-dihydro-5- (trifluoromethyl) -3-isoxazolyl] -3-methyl-N- [ 2-oxo-2 - [(2,2,2-trifluoroethyl) amino] ethyl] -2-thiophenecarboxamide. for use in the prevention of reinfestation of animals by fleas, in which the animal is administered systemically a dose of the isoxazoline compound sufficient to achieve plasma blood concentrations of between 1.5 and 25 ng / ml.
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