| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_459549086df37b5bed0003502de7e7aa |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-803
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5365
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-14 |
| filingDate |
2016-12-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66cdbf1143f390b9c11889e49f2beb4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7111247c74ebca01ba1b8e7fb73cf051
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a83a8c3ed58776932452a84aecf6e73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5fe4ee04222e0dbe3eec6fcfab1a10e2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ef75d1164eef25cb0319e13a6a71565 |
| publicationDate |
2020-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2742249-T3 |
| titleOfInvention |
Process for the preparation of HIV integrase inhibitors |
| abstract |
A process for the preparation of a compound of formula IV ** Formula ** in which P is the hydroxyl protecting group, which comprises reacting a compound of formula XII ** Formula ** in which P is the protecting group of hydroxyl; R1 is H or lower alkyl; R2 and R3 are independently lower alkyl or R2 and R3 may be alkyl and join to form a 5-, 6- or 7-membered ring; R4 is lower alkyl, where lower alkyl is linear or branched alkyl having 1 to 6 carbon atoms; with a compound of formula XVI ** Formula ** to form a compound of formula XVII ** Formula ** and convert a compound of formula XVII ** Formula ** to a compound of formula IV ** Formula ** |
| priorityDate |
2015-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |