abstract |
A modified fHbp V2 having high stability with respect to natural fHbp V2, wherein the modified fHbp V2 has at least 95% identity with SEQ ID ID: 1 and comprises one or more amino acid substitutions at positions equivalent to position 30 , 31, 37, 38, 41, 102, 107, 109, 132 and 133 in SEQ ID ID: 1. |