| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b478d1ad29b562c8c25242c2d718c01f |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4515
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1682
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1629
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5415
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5513
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1647 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 |
| filingDate |
2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2020-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49286f7385346d08053dddae3aea67b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eb48ee5d070e09e551e6db3eceff06a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a744eddd9f3df8bae13fa4709cf96000
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45cd89c07a465c9db1570eb178b107be
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1215f5f7bb808302c7e72c2db9c7285f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47480dba56e086b4a4bfa74deacefe59
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ab5cdbcb765f06df142d1915810eac4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c2c0a8acf5e9c61c55484b7fc21a7f8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ae0162b0e3f9346bbe5c7ac069cd4d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5306603b349efe112ea2638e7ab86f1f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2355c0c1eabe671c78a5307ab963e76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_93d4ff880c8602f0b826c2fa4a6f3bbe |
| publicationDate |
2020-01-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
ES-2738999-T3 |
| titleOfInvention |
Method of preparation of sustained release microparticles containing medicinal products |
| abstract |
A method of preparing sustained-release microparticles containing drugs, comprising: (a) dissolving a biodegradable polymer and a drug in a halogenated alkane solvent to form a biodegradable polymer solution containing a drug; (b) homogeneously mix the biodegradable drug-containing polymer solution in a continuous phase containing a surfactant to form a dispersed phase; (c) maintaining an emulsion including the continuous phase and the dispersed phase at a temperature below the boiling point of the halogenated alkane solvent to form microparticles in the continuous phase; (d) drying the microparticles primarily; (e) mixing the first-dried microparticles with an aqueous-alcoholic solution and maintaining the aqueous-alcoholic solution at a temperature above the boiling point of the halogenated alkane solvent to extract and evaporate the residual halogenated alkane solvent from the microparticles; and (f) secondarily drying the obtained microparticles to produce microparticles containing medicine. |
| priorityDate |
2014-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |