http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2738182-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7e402a6edfe967b9fa48b6e52d50bbe7 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09D139-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09J139-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61J3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09J139-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61J3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09D139-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2014-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2020-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53ca9bc12259d0125714bfa0741623d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_272dfcbd60cd5b224141a7adc5720f09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_01771eb9c50a66499f85b6fcb620fd70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e1c064f07a7c306abbd073b7786270d |
| publicationDate | 2020-01-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2738182-T3 |
| titleOfInvention | Polypropylene Coated Silica Coated Composition |
| abstract | A continuous process to prepare a coprocessed excipient that comprises the steps of: i. deagglomerate the coprocessing agent using a shear at a magnitude of at least 0.01 kWh / kg; wherein the coprocessing agent is selected from fumed silica, colloidal silica, silicon dioxide, calcium silicate, and combinations thereof; ii. passing a polymer derived from the lactam and the deagglomerated coprocessing agent through a mixer with an average particle residence time of> 1 second; wherein the vinyl lactam derived polymer is selected from the group consisting of N-vinyl-2-pyrrolidone, poly (vinyl pyrrolidone), polyvinyl poly pyrrolidone, N-vinyl-2-caprolactam, N-vinyl-3-methyl-2 -pyrrolidone, N-vinyl-3-methyl-2-caprolactam, N-vinyl-4-methyl-2-pyrrolidone, N-vinyl-4-methyl-2-capro-lactam, N-vinyl-5-methyl-2 -pyrrolidone, N-vinyl-5,5-dimethyl-2-pyrrolidone, N-vinyl-3,3,5-trimethyl-2-pyrrolidone, N-vinyl-5-methyl-5-ethyl-2-pyrrolidone, N -vinyl-3,4,5-trimethyl-3-ethyl-2-pyrrolidone, N-vinyl-7-methyl-2-caprolactam, N-vinyl-7-ethyl-2-caprolactam, N-vinyl-3,5 -dimethyl-2-caprolactam, N-vinyl-4,6-dimethyl-2-caprolactam, N-vinyl-3,5,7-trimethyl-2-caprolactam and combinations thereof; iii. subjecting the two previous components to pass through a universal mill; preferably where the universal mill consists of a rotor with a tip speed of 15 meters / second to 150 meters / second and a screen size of 0.2 millimeters to 0.9 millimeters; iv. maintain an average particle residence time within the universal mill system to be> 1 second completed by a continuous recycling process; and V. obtaining the coprocessed excipient having a Brookfield cohesion of less than 0.12 kPa, a bulk density of at least 0.249 grams / milliliter, and a flow property measured by increasing the Johanson flow number from 1.1 to 5, 0 times. |
| priorityDate | 2013-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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Total number of triples: 60.