| abstract |
Use of a sterile injectable aqueous gel of naturally occurring polysaccharide (s) containing hyaluronic acid or one of its salts in an amount of 1 to 100 mg / ml and optionally one or more other polysaccharides of natural origin, and one or more polyols selected from propylene glycol, sorbitol, mannitol alone or in mixture, in an amount of 0.0001 to 100 mg / ml, after autoclaving with heat sterilization of the mixture of polysaccharide (s) and polyol (s ), the gel obtained having a crossover frequency of the elastic modulus G 'and the viscous modulus G' 'comprised between 0 and 10 Hz, preferably between 0.41 ± 0.41 Hz, with G' being higher than G '' at high frequency, for the preparation of an injectable formulation used in the treatment of articular degenerations by intra-articular injection. |