http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2729707-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_585ae80bdf494750db2409ac8c811898 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D501-57 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P17-184 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-04 |
| filingDate | 2012-06-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd354aa7606bbeec5bbfd3caf1a97578 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f70b17cc4f909dfd9b48eca5456d3b8c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed26cb99c726eaf96691c39ef4355a86 |
| publicationDate | 2019-11-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2729707-T3 |
| titleOfInvention | Process of preparation of 3'-thiosubstituted cephalosporins using a penicillin G acylase |
| abstract | A process for the preparation of a compound of the general formula (1) ** Formula ** in which R1 is a radical of the formula (2a), (2b), (2c), (2d), (2e) or (2f), where R3 is CH3, CH2CO2H, CH2SO3H, CH2CH2OH or CH2CH2N (CH3) 2 and R4 is hydrogen or CH3 ** Formula ** and in which R2 is H or OH and X is CH2, O or S, characterized in that a compound of the general formula (3) or a salt thereof in which R1 and X are as defined above is mixed ** Formula ** with D-4-hydroxyphenylglycine amide or a D-4-hydroxyphenylglycine ester or D-phenylglycine amide or a diphenylglycine ester in the presence of a penicillin G acylase at a temperature of from -5 ° C to 20 ° C and a pH range of 8.4 to 9.1. |
| priorityDate | 2011-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.