http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2729111-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C01B25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-00 |
| filingDate | 2012-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb388a0c60e458e2d122364b64804dec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e02572cd22d946766364e82cb64e78a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6077725c3c84504cddc094fa240f7f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acc1f14fc606b3d31fb839a2ff696470 |
| publicationDate | 2019-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2729111-T3 |
| titleOfInvention | Method for the preparation of aluminum hydroxyphosphate adjuvant |
| abstract | A method for the preparation of aluminum hydroxyphosphate adjuvant comprising the steps of: (a) jointly mixing a solution of an aluminum salt with a solution of a phosphate in a defined P / Al molar ratio and in the presence of a buffer maintaining a constant pH, wherein said mixture involves the simultaneous and continuous combination of the solution of the aluminum salt and the phosphate solution in a constant reagent ratio; where the defined P / Al ratio is in the range of 2.0-3.5; wherein the phosphate solution has a pH of 7.4 to 12.4, 8.0 to 10.0, or 8.5 to 9.5; and where the buffer is the same as the phosphate solution; and (b) exchange the buffer with a buffer exchange solution to remove at least 80% of any excess phosphate, buffer or other residual salts from the original reagents. |
| priorityDate | 2011-11-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 130.