| abstract |
A viral expression vector comprising a genome of the paralympic virus 5 (PIV5) comprising a heterologous nucleotide sequence that expresses a heterologous polypeptide, in which the heterologous nucleotide sequence is inserted between the small hydrophobic protein (SH) gene and the hemagglutinin-neuroaminidase (HN) gene of the PIV5 genome, and in which the heterologous polypeptide comprises a influenza hemagglutinin (HA), for use in the prevention of influenza infection. |