http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2727594-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_404c00c90c2319f6261b57f2a3ccd77c http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_37ff2ea5296ce316e0cee7dd3181fa4a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5078 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1676 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-436 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-436 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
| filingDate | 2011-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_422728295415fd2014db81758459493e |
| publicationDate | 2019-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2727594-T3 |
| titleOfInvention | Sustained-release granules containing tacrolimus as active ingredient |
| abstract | Sustained-release granules containing tacrolimus as the active ingredient and consisting of: - a layer of active pharmacological ingredient (B1) containing tacrolimus as the main ingredient and hydroxypropyl methylcellulose as a binder around the core (A); - a layer of primary pharmacological inactive ingredient (C1) surrounding said layer of pharmacological active ingredient and containing hydroxypropyl methylcellulose; - a sustained release layer (D) surrounding said primary pharmacological inactive ingredient layer and containing Surelease™ (SURELEASE NG E-7-19050; solid) and hydroxypropyl methylcellulose; - a layer of secondary pharmacological inactive ingredient (C2) surrounding said sustained release layer and containing hydroxypropyl methylcellulose; and - an initial release membrane layer (B2) surrounding said secondary pharmacological inactive ingredient layer and containing tacrolimus and hydroxypropyl methylcellulose; - characterized in that the weight ratio of tacrolimus:hydroxypropyl methylcellulose:SureleaseTm (SURELEASE NG E-7-19050; solids) in said granules is 1:10-15:3.6-4.8. |
| priorityDate | 2010-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 60.