http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2726946-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9df2faf626ee27afc7732852a857d0fd |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2300-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-425 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-337 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4192 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-427 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-428 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-2013 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-538 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-517 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7068 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-426 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-427 |
| filingDate | 2010-01-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6bd6088bd4cc069d8d5955fd2dbf87c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4f0736151ddcf6e7532b45d8672a07e |
| publicationDate | 2019-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2726946-T3 |
| titleOfInvention | Benzosulfonamide derivatives, compositions thereof and their use in the prevention of cancer cell metastasis |
| abstract | A compound for use in the prevention, remission, minimization, control and / or attenuation of tumor metastasis in a human being who has a glioma, a compound that has the formula I: ** Formula ** in which R is a substituted or unsubstituted thiazolyl unit having the formula: ** Formula ** R2, R3 and R4 are each independently: i) hydrogen; ii) substituted or unsubstituted linear, branched or cyclic C1-C6 alkyl; iii) C2-C6 linear, branched or cyclic substituted or unsubstituted alkenyl; iv) substituted or unsubstituted linear or branched C2-C6 alkynyl; v) substituted or unsubstituted C6 or C10 aryl; vi) substituted or unsubstituted C1-C9 heteroaryl; iv) substituted or unsubstituted C1-C9 heterocyclic; or viii) R2 and R3 together form a saturated or unsaturated ring having 5 to 7 atoms; wherein 1 to 3 atoms may optionally be heteroatoms selected from oxygen, nitrogen and sulfur; Z is a unit having the formula: R1 is selected from: i) hydrogen; ii) hydroxyl; iii) amino; iv) substituted or unsubstituted linear, branched or cyclic C1-C6 alkyl; v) C1-C6 linear, branched or cyclic substituted or unsubstituted alkoxy; vi) C6 or C10 substituted or unsubstituted aryl; iv) substituted or unsubstituted C1-C9 heterocyclic; or viii) substituted or unsubstituted C1-C9 heteroaryl; L is a linker unit having the formula: - [Q] and [C (R5aR5b)] x [Q1] z [C (R6aR6b)] wcada Q and Q1 is independently: i) -C (O) -; ii) -NH-; iii) -C (O) NH-; iv) -NHC (O) -; v) -NHC (O) NH-; vi) -NHC (O) O-; vii) -C (O) O-; viii) -C (O) NHC (O) -; ix) -O-; x) -S-; xi) -SO2-; xii) -C (= NH) -; xiii) -C (= NH) NH-; xiv) -NHC (= NH) -; or xv) -NHC (= NH) NH-; each R5a and R5b is independently: i) hydrogen; ii) hydroxy; iii) halogen; iv) substituted or unsubstituted linear or branched C1-C6 alkyl; or v) a unit having the formula: - [C (R7aR7b)] tR8 each R7a and R7b is independently: i) hydrogen; or ii) substituted, unsubstituted linear, branched or cyclic C1-C6 alkyl; R8 is: i) hydrogen; ii) substituted or unsubstituted linear, branched or cyclic C1-C6 alkyl; iii) C6 or C10 substituted or unsubstituted aryl; iv) substituted or unsubstituted C1-C9 heteroaryl; or v) substituted or unsubstituted C1-C9 heterocyclic; each R6a and R6b is independently: i) hydrogen; or ii) linear or branched C1-C4 alkyl; the index n is 0 or 1; the indices t, w and x are each independently from 0 to 4; the indices y and z are each independently 0 or 1; or a pharmaceutically acceptable salt thereof. |
| priorityDate | 2009-07-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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