| abstract |
An anti-interleukin-17F (IL-17F) human monoclonal antibody, or antigen-binding fragment thereof, in which the antibody recognizes a conformational epitope in IL-17F and is capable of neutralizing the biological activity of IL-17F , and the antibody or antigen binding fragment thereof, comprises in its variable heavy chain (VH) and in its variable light chain (VL), the amino acid sequence of the VH and VL chain of SEQ ID NO: 15 and 17, respectively, or of SEQ ID NO: 23 and 25, respectively. |