http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2726152-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7a8c997f15e4c1f6392a7ea329823eb1 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4709 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4545 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5025 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-437 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d3bd57fff6b135879b3b85e3fe1e1ca http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_26dd2d5bf560ba728b3af1708d4b817d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3550cc08804a42b22b5450210dfae815 |
| publicationDate | 2019-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2726152-T3 |
| titleOfInvention | Certain triazolopyridines, their compositions and their use in the treatment of cancer |
| abstract | At least one compound of formula 1: ** Formula ** and / or at least one of its pharmaceutically acceptable salts wherein: X is C (R6), Y is selected from -O-, -S-, and -N ( R7) - or Y is absent, and R1 is 8-10 membered heteroaryl optionally substituted with one or more groups selected from halo, -CF3, -CF2H, cycloalkyl, -C (O) R11, -C (O) OR11, -CN, - C (O) NR13R14, -NR13R14, -NR13C (O) R11, - NR13S (O) nR12, -NR13S (O) nNR13R14, -NR13C (O) OR12, -NR13C (O) NR13R14, - NO2 , -S (O) nR12, - S (O) nNR13R14, heterocycle, heteroaryl, aryl, alkenyl, alkynyl, a linear or branched hydrocarbon containing 1-4 carbon atoms, a linear or branched hydrocarbon containing 1-4 atoms carbon substituted with hydroxy, a linear or branched hydrocarbon containing 1-4 carbon atoms substituted with a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, a linear or branched hydrocarbon containing 1-4 carbon atoms substituted with -NR13R14, and a hydr linear or branched ocarbide containing 1-4 carbon atoms substituted with heterocycle; R2 and R3 are independently selected from hydrogen, and alkyl, or R2 and R3, together with the carbon to which they are attached, form a ring selected from 3 to 7 membered cycloalkyl and 3 to 7 membered heterocycle; R4 is selected from halo, alkyl, cycloalkyl, heterocycle, aryl and heteroaryl, each of which, except the halo, is optionally substituted with one or more groups selected from a linear or branched hydrocarbon containing 1-4 optionally carbon atoms substituted with one or more groups selected from hydroxy, a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, cyano, halo, -C (O) OR11, -C (O) NR13R14, - NR13R14, - OC (O) R11, -NR13C (O) R11, -NR13S (O) nR12, -NR13S (O) nNR13R14, -NR13C (O) OR12, and - NR13C (O) NR13R14, a linear or branched alkoxy, in wherein the alkyl portion contains 1-4 carbon atoms optionally substituted with one or more groups selected from halo, hydroxy, and a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, cycloalkoxy optionally substituted with one or more groups selected from halo, hydroxy, and a linear or branched alkoxy, in which the alkyl portion contains 1-4 carbon atoms, heterocycloalkoxy optionally substituted with one or more groups selected from halo, hydroxy, and a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, heterocycle optionally substituted with one or more groups selected from a linear or branched hydrocarbon containing 1-4 carbon atoms, halo, hydroxy, and a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, heteroaryloxy optionally substituted with one or more groups selected from a linear or branched hydrocarbon containing 1-4 carbon atoms, halo, hydroxy, and a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, aryl optionally substituted with one or more selected groups of a linear or branched hydrocarbon containing 1-4 carbon atoms, halo, hydroxy, and a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms , heteroaryl optionally substituted with one or more groups selected from a linear or branched hydrocarbon containing 1-4 carbon atoms, halo, hydroxy, and a linear or branched alkoxy, wherein the alkyl portion contains 1-4 carbon atoms, halo, cyano, -C (O) R11, -C (O) OR11, -NR13R14, -NR13C (O) R11, -NR13S (O) nR12, - NR13S (O) nNR13R14, -NR13C (O) OR12, - NR13C (O) NR13R14, -C (O) NR13R14, S (O) nR12, and S (O) nNR13R14; R5 is selected from hydrogen, halo, OH, NH2, CF3, -CF2H, alkyl, alkenyl and alkynyl; R6 is selected from hydrogen, -OH, -NH2, -NHC (O) R11, halo and alkyl; R7 is selected from hydrogen and a linear or branched hydrocarbon containing 1-4 carbon atoms; each n is independently 0, 1, or 2; |
| priorityDate | 2009-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 478.