http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2724206-T3
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7c5e77c181522ee1fd44df1ae5ac2196 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D409-12 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D409-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D495-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
filingDate | 2013-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2019-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_446b04edff2c49aaff2cc9c05c4ac2d0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa5310508fb84b4db6adfe9b83e099c9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd32c2c9df246460a35414dceb8fdc1a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc1545ac50f2df8ebd9633d55a922ade |
publicationDate | 2019-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | ES-2724206-T3 |
titleOfInvention | Production method of a thienopyrimidine derivative |
abstract | A production method of 1- {4- [1- (2,6-Difluorobenzyl) -5-dimethylaminomethyl-3- (6-methoxypyridazin-3-yl) -2,4-dioxo-1,2,3,4 -tetrahydrothiene [2,3-d] pyrimidin-6-yl] phenyl} -3-methoxyurea or a salt thereof, comprising reacting 6- (4-aminophenyl) -1- (2,6-difluorobenzyl) - 5-dimethylaminomethyl-3- (6-methoxypyridazin-3-yl) thieno [2,3-d] pyrimidin-2,4 (1H, 3H) -dione or a salt thereof, 1,1'-carbonyldiimidazole or a salt thereof and methoxyamine or a salt thereof, wherein 1,1'carbonyldiimidazole or a salt thereof is used in an amount of 1.6 to 2.5 equivalents with respect to 6- (4-aminophenyl) - 1- (2,6-Difluorobenzyl) -5-dimethylaminomethyl-3- (6-methoxypyridazin-3-yl) thieno [2,3-d] pyrimidin-2,4 (1H, 3H) -dione or a salt of the itself and methoxyamine or a salt thereof is used in an amount of 1.0 to 1.5 equivalents with respect to 1,1'-carbonyldiimidazole or a salt thereof. |
priorityDate | 2012-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 111.