http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2715378-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6012ce2ccf64fbc34ba201c9f11ada92 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-73 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18534 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2760-18522 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-55561 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-155 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N7-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-155 |
| filingDate | 2014-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_718a990d4dfd80790eab74074316a863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ba681f4d91b948c5ca4940425fcd4120 |
| publicationDate | 2019-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2715378-T3 |
| titleOfInvention | Soluble and stabilized respiratory syncytial virus (RSV) prefusion polypeptides |
| abstract | A recombinant respiratory syncytial virus (RSV) prefusion fusion (F) polypeptide, comprising at least one epitope that has specificity for the prefusion conformation protein F, where the at least one epitope is recognized by a monoclonal antibody with specificity for the prefusion conformation comprising a CDR1 region of the heavy chain such as that represented in SEQ ID No. 54, a CDR2 region of the heavy chain such as that represented in SEQ ID No. 55, a CDR3 region of the chain Weighted as the one represented in SEQ ID No. 56, a CDR1 region of the light chain such as the one represented in SEQ ID No. 62, a CDR2 region of the light chain such as that represented in SEQ ID No. 63 and a region CDR3 of the light chain as depicted in SEQ ID No. 64, and / or is recognized by a monoclonal antibody with specificity for the prefusion conformation comprising a CDR1 region of the heavy chain such as the which is represented in SEQ ID No. 58, a CDR2 region of the heavy chain such as that represented in SEQ ID No. 59, a CDR3 region of the heavy chain such as that represented in SEQ ID No. 60, a CDR1 region of the light chain like the one represented in SEQ ID No. 66, a CDR2 region of the light chain like the one represented in SEQ ID No. 67 and a CDR3 region of the light chain like the one represented in SEQ ID No. 68, where the polypeptide comprises a mutation of the amino acid residue N / T at position 67 to I and / or a mutation of amino acid residue S at position 215 to P, where amino acid positions are provided in reference to the protein sequence RSV F of strain A2 (SEQ ID NO: 1). |
| priorityDate | 2013-04-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 103.