abstract |
A bioerodible polymer-bioactive agent conjugate comprising, as part of its polymeric backbone, a moiety of general formula (I): ** Formula ** wherein: A and B, which may be the same or different, represent all of the The rest of the polymer backbone and (i) are attached to the moiety -OR (ZD) -O- as shown in formula (I) through a bioerodible moiety, and (ii) comprise a poly (urethane-ester) which possesses monomer units coupled through bioerodible urethane or ester residues; R represents an optionally substituted straight or branched hydrocarbon; Z is a linking group; and D is a releasable bioactive agent. |