| abstract |
A pharmaceutical composition in the form of a tablet with an optional film coating containing a) a therapeutically effective amount of the sodium salt of the trans- (4- {4- [5- (6-trifluoromethyl-pyridin- 3- ilamino) -pyridin-2-yl] -phenyl} -cyclohexyl) -acetic acid of formula (I), ** Formula ** b) sodium lauryl sulfate as a surfactant with lubricating properties, wherein said surfactant is present in an amount between 0.1 and 5% by weight of the tablet, before any optional film coating and based on the free acid of the compound of formula (I); c) hydroxypropylmethylcellulose or hydroxypropylcellulose, both of medium to high viscosity, and combinations thereof, as dry binder, wherein said dry binder is present in an amount between 2 and 20% by weight of the tablet, before any optional film-based coating in the free acid of the compound of formula (I); d) a filler chosen from microcrystalline cellulose, anhydrous dicalcium phosphate, anhydrous lactose and mixtures thereof, and a combination of microcrystalline cellulose and anhydrous dicalcium phosphate, and a combination of microcrystalline cellulose and lactose, and wherein said filler is present in an amount between 4% and 85% by weight of the tablet, before any optional film coating and based on the free acid of the compound of formula (I), and) starch sodium glycolate as a disintegrant, wherein said disintegrant is present in an amount between 1 and 10% by weight of the tablet, before any optional film coating and based on the free acid of the compound of formula (I). |