http://rdf.ncbi.nlm.nih.gov/pubchem/patent/ES-2712060-T3
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_529fd92fff922bfbbfe8837b647cca76 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-168 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-564 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-564 |
| filingDate | 2011-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43d42ce031429408073d5d70c458968f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07c518b368fa7e515b251efc09cb8d35 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5949b8444300eefece7689768faed532 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e9d812a9e451392b71c64b4dcbf8ee1 |
| publicationDate | 2019-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | ES-2712060-T3 |
| titleOfInvention | Diagnostic methods for glaucoma |
| abstract | A method for the diagnosis of glaucoma comprising the steps of: (a) providing at least two samples comprising at least one at least partially purified eye antigen, thus providing together at least two at least partially purified eye antigens or providing at least one sample comprising at least two at least partially purified eye antigens, in which the at least two at least partially purified eye antigens are selected from a Group 1 of ocular antigens comprising the following ocular antigens: actin, albumin, alpha 1- antitrypsin, annexin l-IV, annexin V, beta 2 adrenergic receptor, brain-derived neurotrophic factor (BDNF), calreticulin, cardiolipin, crystalline alpha-A, crystalline alpha-B, crystalline beta-L, crystalline beta-S, crystalline gamma , DNA topoisomerase 1, fibronectin, α-fodrine (= spectrin), glial fibrillary acidic protein (GFAP), glutathione-Stransferase, prote Heat shock pathway HSP10 (= chaperonin), HSP27, HSP60, HSP70, insulin, jo-1, lysozyme, myelin-binding protein (MBP), oligodendrocyte myelin glycoprotein (MOG), myoglobin, neuron-specific enolase ( NSE), neurotrophin 3, neurotrophin 4, neurotrophin 5, superoxide dismutase, 3-phosphoserine, prealbumin, protein C kinase inhibitor, protein C kinase, superoxide dismutase, alpha-synuclein, gamma-synuclein, thyroglobulin, transferrin , transthyretin, topoisomerase inhibitor, ubiquitin, vascular endothelial growth factor (VEGF), vimentin, (b) contacting a body fluid with the sample or samples provided in stage a) comprising at least two purified ocular antigens at least partially, (c) detect and / or quantify the reactions of step b) between the body fluid autoantibodies and the at least two ocular antigens partially purified in the sample or samples p For the determination of an autoimmune reactivity value, (d) compare the measured values of the autoimmune reactivity with the conventional data obtained from glaucoma patients and optionally additionally from healthy individuals, for the determination of a glaucoma score and ( e) optionally determine a diagnostic result by evaluating the glaucoma score. |
| priorityDate | 2010-04-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1711.